Indeed. See also: Wyatt's wife in Tombstone.
100 proof alcohol + opium. That's class all the way. (and it would fit my Victoriana fetish too!)
For the alternate effect:
![Image](http://cacb.files.wordpress.com/2010/09/leo_xiii_ad1.gif)
![Image](http://cocaine.org/vinmariani.jpg)
Wine full of blow. How many fucking records would I have out now if I could just go to the liquor store and buy that shit?